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Association between EBV serological patterns and lymphocytic profile of SjS patients support a virally triggered autoimmune epithelitis

Sjögren's syndrome (SjS) is characterized by lymphocytic infiltration of exocrine glands, i.e. autoimmune epithelitis. Lymphocytes are central in SjS pathogenesis, with B-cell hyperactivity mediated by T-cells. B-cells are main targets of Epstein-Barr virus (EBV) infection, a frequently-suggest...

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Detalles Bibliográficos
Autores principales: Barcelos, Filipe, Martins, Catarina, Monteiro, Ricardo, Cardigos, Joana, Prussiani, Tiziano, Sítima, Miguel, Alves, Nuno, Vaz-Patto, José, Cunha-Branco, Jaime, Borrego, Luís-Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893064/
https://www.ncbi.nlm.nih.gov/pubmed/33603079
http://dx.doi.org/10.1038/s41598-021-83550-0