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Association between EBV serological patterns and lymphocytic profile of SjS patients support a virally triggered autoimmune epithelitis
Sjögren's syndrome (SjS) is characterized by lymphocytic infiltration of exocrine glands, i.e. autoimmune epithelitis. Lymphocytes are central in SjS pathogenesis, with B-cell hyperactivity mediated by T-cells. B-cells are main targets of Epstein-Barr virus (EBV) infection, a frequently-suggest...
Autores principales: | Barcelos, Filipe, Martins, Catarina, Monteiro, Ricardo, Cardigos, Joana, Prussiani, Tiziano, Sítima, Miguel, Alves, Nuno, Vaz-Patto, José, Cunha-Branco, Jaime, Borrego, Luís-Miguel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893064/ https://www.ncbi.nlm.nih.gov/pubmed/33603079 http://dx.doi.org/10.1038/s41598-021-83550-0 |
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