Phosphorylation regulates cullin-based ubiquitination in tumorigenesis

Cullin-RING ligases (CRLs) recognize and interact with substrates for ubiquitination and degradation, and can be targeted for disease treatment when the abnormal expression of substrates involves pathologic processes. Phosphorylation, either of substrates or receptors of CRLs, can alter their intera...

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Detalles Bibliográficos
Autores principales: Chen, Yifan, Shao, Xuejing, Cao, Ji, Zhu, Hong, Yang, Bo, He, Qiaojun, Ying, Meidan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893081/
https://www.ncbi.nlm.nih.gov/pubmed/33643814
http://dx.doi.org/10.1016/j.apsb.2020.09.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893081/
https://www.ncbi.nlm.nih.gov/pubmed/33643814
http://dx.doi.org/10.1016/j.apsb.2020.09.007

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