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Phosphorylation regulates cullin-based ubiquitination in tumorigenesis
Cullin-RING ligases (CRLs) recognize and interact with substrates for ubiquitination and degradation, and can be targeted for disease treatment when the abnormal expression of substrates involves pathologic processes. Phosphorylation, either of substrates or receptors of CRLs, can alter their intera...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893081/ https://www.ncbi.nlm.nih.gov/pubmed/33643814 http://dx.doi.org/10.1016/j.apsb.2020.09.007 |