Cargando…

Phosphorylation regulates cullin-based ubiquitination in tumorigenesis

Cullin-RING ligases (CRLs) recognize and interact with substrates for ubiquitination and degradation, and can be targeted for disease treatment when the abnormal expression of substrates involves pathologic processes. Phosphorylation, either of substrates or receptors of CRLs, can alter their intera...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Yifan, Shao, Xuejing, Cao, Ji, Zhu, Hong, Yang, Bo, He, Qiaojun, Ying, Meidan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893081/ https://www.ncbi.nlm.nih.gov/pubmed/33643814 http://dx.doi.org/10.1016/j.apsb.2020.09.007

Ejemplares similares

Inhibition of Ubiquitin-Specific Proteases as a Novel Anticancer Therapeutic Strategy
por: Yuan, Tao, et al.
Publicado: (2018)

Flexible Cullins in Cullin-RING E3 Ligases Allosterically Regulate Ubiquitination
por: Liu, Jin, et al.
Publicado: (2011)

Cullin-RING ubiquitin ligases: global regulation and activation cycles
por: Bosu, Dimple R, et al.
Publicado: (2008)

Regulation of cell cycle drivers by Cullin-RING ubiquitin ligases
por: Jang, Sang-Min, et al.
Publicado: (2020)

The structure and regulation of Cullin 2 based E3 ubiquitin ligases and their biological functions
por: Cai, Weijia, et al.
Publicado: (2016)

The role of cullin 5-containing ubiquitin ligases
por: Okumura, Fumihiko, et al.
Publicado: (2016)

The HER2 inhibitor TAK165 Sensitizes Human Acute Myeloid Leukemia Cells to Retinoic Acid-Induced Myeloid Differentiation by activating MEK/ERK mediated RARα/STAT1 axis
por: Shao, Xuejing, et al.
Publicado: (2016)

Skp-cullin-F box E3 ligase component FBXL2 ubiquitinates Aurora B to inhibit tumorigenesis
por: Chen, B B, et al.
Publicado: (2013)

Roles of Cullin-RING Ubiquitin Ligases in Cardiovascular Diseases
por: Diaz, Stephanie, et al.
Publicado: (2022)

Regulation of Cullin RING E3 Ubiquitin Ligases by CAND1 In Vivo
por: Chua, Yee Shin, et al.
Publicado: (2011)

Trade-off and flexibility in the dynamic regulation of the cullin-RING ubiquitin ligase repertoire
por: Straube, Ronny, et al.
Publicado: (2017)

Cullin Family Proteins and Tumorigenesis: Genetic Association and Molecular Mechanisms
por: Chen, Zhi, et al.
Publicado: (2015)

Cullin 4b-RING ubiquitin ligase targets IRGM1 to regulate Wnt signaling and intestinal homeostasis
por: Fan, Yujia, et al.
Publicado: (2022)

Blockade of deubiquitinase YOD1 degrades oncogenic PML/RARα and eradicates acute promyelocytic leukemia cells
por: Shao, Xuejing, et al.
Publicado: (2022)

Mechanism of Cullin3 E3 Ubiquitin Ligase Dimerization
por: Choo, Yin Yin, et al.
Publicado: (2012)

Importance of Cullin4 Ubiquitin Ligase in Malignant Pleural Mesothelioma
por: Meerang, Mayura, et al.
Publicado: (2020)

The E3 Ubiquitin-Protein Ligase Cullin 3 Regulates HIV-1 Transcription
por: Langer, Simon, et al.
Publicado: (2020)

WSB1 regulates c-Myc expression through β-catenin signaling and forms a feedforward circuit
por: Gao, Xiaomeng, et al.
Publicado: (2022)

Cullin-4B E3 ubiquitin ligase mediates Apaf-1 ubiquitination to regulate caspase-9 activity
por: Ohta, Eri, et al.
Publicado: (2019)

Characterization of the role of COP9 signalosome in regulating cullin E3 ubiquitin ligase activity
por: Choo, Yin Yin, et al.
Publicado: (2011)

Regulation of Cullin-RING ubiquitin ligase 1 by Spliceosome-associated protein 130 (SAP130)
por: Cordero-Espinoza, Lucia, et al.
Publicado: (2013)

The Role of the Cullin-5 E3 Ubiquitin Ligase in the Regulation of Insulin Receptor Substrate-1
por: Hu, Christine Zhiwen, et al.
Publicado: (2012)

Cullin-3 and the endocytic system: New functions of ubiquitination for endosome maturation
por: Hubner, Michaela, et al.
Publicado: (2012)

Cullin 3 Ubiquitin Ligases in Cancer Biology: Functions and Therapeutic Implications
por: Chen, Hsin-Yi, et al.
Publicado: (2016)

It is not all about BRCA: Cullin-Ring ubiquitin Ligases in ovarian cancer
por: Carlucci, A, et al.
Publicado: (2015)

The functional analysis of Cullin 7 E3 ubiquitin ligases in cancer
por: Shi, Le, et al.
Publicado: (2020)

Determining the Effects of Neddylation on Cullin‐RING Ligase–Dependent Protein Ubiquitination
por: Wang, Kankan, et al.
Publicado: (2022)

Identification of hypertrophy-modulating Cullin-RING ubiquitin ligases in primary cardiomyocytes
por: Fischer, Maximillian, et al.
Publicado: (2023)

Cullin 2-RBX1 E3 ligase and USP2 regulate antithrombin ubiquitination and stability
por: Xu, Dacai, et al.
Publicado: (2021)

The Role of Membrane-Associated E3 Ubiquitin Ligases in Cancer
por: Chen, Xuankun, et al.
Publicado: (2022)

Cullin 3(SPOP) ubiquitin E3 ligase promotes the poly-ubiquitination and degradation of HDAC6
por: Tan, Yuyong, et al.
Publicado: (2017)

CAND1 controls in vivo dynamics of the Cullin 1-RING ubiquitin ligase repertoire
por: Wu, Shuangding, et al.
Publicado: (2013)

The ubiquitin ligase Cullin-1 associates with chromatin and regulates transcription of specific c-MYC target genes
por: Sweeney, Melanie A., et al.
Publicado: (2020)

DJ-1 suppresses ferroptosis through preserving the activity of S-adenosyl homocysteine hydrolase
por: Cao, Ji, et al.
Publicado: (2020)

Cullin4 E3 Ubiquitin Ligases Regulate Male Gonocyte Migration, Proliferation and Blood-Testis Barrier Homeostasis
por: Yin, Yan, et al.
Publicado: (2021)

Cullin-RING ubiquitin ligases in salicylic acid-mediated plant immune signaling
por: Furniss, James J., et al.
Publicado: (2015)

Cellular Cullin RING Ubiquitin Ligases: Druggable Host Dependency Factors of Cytomegaloviruses
por: Becker, Tanja, et al.
Publicado: (2019)

Inhibitors of cullin-RING E3 ubiquitin ligase 4 with antitumor potential
por: Wu, Kenneth, et al.
Publicado: (2021)

Inhibition of KLF4 by Statins Reverses Adriamycin-Induced Metastasis and Cancer Stemness in Osteosarcoma Cells
por: Li, Yangling, et al.
Publicado: (2017)

Inhibition of KLF4 by Statins Reverses Adriamycin-Induced Metastasis and Cancer Stemness in Osteosarcoma Cells
por: Li, Yangling, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_mtd8hameoginion7dsgj7mp6ol