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Systematic Evaluation of Kinetics and Distribution of Muscle and Lymph Node Activation Measured by (18)F-FDG- and (11)C-PBR28-PET/CT Imaging, and Whole Blood and Muscle Transcriptomics After Immunization of Healthy Humans With Adjuvanted and Unadjuvanted Vaccines

Systems vaccinology has been applied to detect signatures of human vaccine induced immunity but its ability, together with high definition in vivo clinical imaging is not established to predict vaccine reactogenicity. Within two European Commission funded high impact programs, BIOVACSAFE and ADITEC,...

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Detalles Bibliográficos
Autores principales: Win, Zarni, Weiner 3rd, January, Listanco, Allan, Patel, Neva, Sharma, Rohini, Greenwood, Aldona, Maertzdorf, Jeroen, Mollenkopf, Hans-Joachim, Pizzoferro, Kat, Cole, Thomas, Bodinham, Caroline L., Kaufmann, Stefan H. E., Denoel, Philippe, Del Giudice, Giuseppe, Lewis, David J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893084/
https://www.ncbi.nlm.nih.gov/pubmed/33613536
http://dx.doi.org/10.3389/fimmu.2020.613496