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Systematic Evaluation of Kinetics and Distribution of Muscle and Lymph Node Activation Measured by (18)F-FDG- and (11)C-PBR28-PET/CT Imaging, and Whole Blood and Muscle Transcriptomics After Immunization of Healthy Humans With Adjuvanted and Unadjuvanted Vaccines
Systems vaccinology has been applied to detect signatures of human vaccine induced immunity but its ability, together with high definition in vivo clinical imaging is not established to predict vaccine reactogenicity. Within two European Commission funded high impact programs, BIOVACSAFE and ADITEC,...
Autores principales: | Win, Zarni, Weiner 3rd, January, Listanco, Allan, Patel, Neva, Sharma, Rohini, Greenwood, Aldona, Maertzdorf, Jeroen, Mollenkopf, Hans-Joachim, Pizzoferro, Kat, Cole, Thomas, Bodinham, Caroline L., Kaufmann, Stefan H. E., Denoel, Philippe, Del Giudice, Giuseppe, Lewis, David J. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893084/ https://www.ncbi.nlm.nih.gov/pubmed/33613536 http://dx.doi.org/10.3389/fimmu.2020.613496 |
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