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Microbiota as Drivers and as Therapeutic Targets in Ocular and Tissue Specific Autoimmunity

Autoimmune uveitis is a major cause of blindness in humans. Activation of retina-specific autoreactive T cells by commensal microbiota has been shown to trigger uveitis in mice. Although a culprit microbe and/or its immunogenic antigen remains to be identified, studies from inducible and spontaneous...

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Detalles Bibliográficos
Autores principales: Salvador, Ryan, Zhang, Amy, Horai, Reiko, Caspi, Rachel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893107/
https://www.ncbi.nlm.nih.gov/pubmed/33614621
http://dx.doi.org/10.3389/fcell.2020.606751