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Gadd45b is required in part for the anti-obesity effect of constitutive androstane receptor (CAR)
Crosstalk between xenobiotic metabolism and energy metabolism in the liver has provided a potential opportunity to target xenobiotic receptors to treat metabolic diseases. Activation of constitutive androstane receptor (CAR), a xenobiotic-sensing nuclear receptor, has been shown to inhibit obesity,...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893119/ https://www.ncbi.nlm.nih.gov/pubmed/33643822 http://dx.doi.org/10.1016/j.apsb.2020.08.015 |