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SUV39H1 deficiency suppresses clear cell renal cell carcinoma growth by inducing ferroptosis

Clear cell renal cell carcinoma (ccRCC) is a common kidney malignancy characterized by a poor prognosis. Suppressor of variegation 3–9 homolog 1 (SUV39H1), which encodes a histone H3 lysine 9 methyltransferase, has been reported to act as an oncogene in many cancers. However, it is unclear whether S...

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Detalles Bibliográficos
Autores principales: Wang, Jianfeng, Yin, Xiaomao, He, Wei, Xue, Wei, Zhang, Jin, Huang, Yiran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893126/
https://www.ncbi.nlm.nih.gov/pubmed/33643820
http://dx.doi.org/10.1016/j.apsb.2020.09.015