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A four-protein metabolon assembled by a small peptide protein creates the pentacyclic carbonate ring of aldgamycins

Organic carbonates (OCs) are a class of compounds featured by a carbonyl flanked by two alkoxy/aryloxy groups. They exist in either linear or cyclic forms, of which the majority encountered in nature adopt a pentacyclic structure. However, the enzymatic basis for pentacyclic carbonate ring formation...

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Detalles Bibliográficos
Autores principales: Wang, Qiaozhen, Tang, Xiaolong, Dai, Ping, Wang, Chuanxi, Zhang, Weiyang, Chen, Guodong, Hong, Kui, Hu, Dan, Gao, Hao, Yao, Xinsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893128/
https://www.ncbi.nlm.nih.gov/pubmed/33643833
http://dx.doi.org/10.1016/j.apsb.2020.07.015