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Spatiotemporally programmable cascade hybridization of hairpin DNA in polymeric nanoframework for precise siRNA delivery

DNA nanostructures have been demonstrated as promising carriers for gene delivery. In the carrier design, spatiotemporally programmable assembly of DNA under nanoconfinement is important but has proven highly challenging due to the complexity–scalability–error of DNA. Herein, a DNA nanotechnology-ba...

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Detalles Bibliográficos
Autores principales: Li, Feng, Yu, Wenting, Zhang, Jiaojiao, Dong, Yuhang, Ding, Xiaohui, Ruan, Xinhua, Gu, Zi, Yang, Dayong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893159/
https://www.ncbi.nlm.nih.gov/pubmed/33602916
http://dx.doi.org/10.1038/s41467-021-21442-7