VEGFR2-targeted antibody fused with IFNαmut regulates the tumor microenvironment of colorectal cancer and exhibits potent anti-tumor and anti-metastasis activity

Although interferon α (IFNα) and anti-angiogenesis antibodies have shown appropriate clinical benefit in the treatment of malignant cancer, they are deficient in clinical applications. Previously, we described an anti-vascular endothelial growth factor receptor 2 (VEGFR2)-IFNα fusion protein named J...

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Detalles Bibliográficos
Autores principales: Shang, Pengzhao, Gao, Rui, Zhu, Yijia, Zhang, Xiaorui, Wang, Yang, Guo, Minji, Peng, Hui, Wang, Min, Zhang, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893194/
https://www.ncbi.nlm.nih.gov/pubmed/33643821
http://dx.doi.org/10.1016/j.apsb.2020.09.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893194/
https://www.ncbi.nlm.nih.gov/pubmed/33643821
http://dx.doi.org/10.1016/j.apsb.2020.09.008

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