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VEGFR2-targeted antibody fused with IFNαmut regulates the tumor microenvironment of colorectal cancer and exhibits potent anti-tumor and anti-metastasis activity

Although interferon α (IFNα) and anti-angiogenesis antibodies have shown appropriate clinical benefit in the treatment of malignant cancer, they are deficient in clinical applications. Previously, we described an anti-vascular endothelial growth factor receptor 2 (VEGFR2)-IFNα fusion protein named J...

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Detalles Bibliográficos
Autores principales:	Shang, Pengzhao, Gao, Rui, Zhu, Yijia, Zhang, Xiaorui, Wang, Yang, Guo, Minji, Peng, Hui, Wang, Min, Zhang, Juan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893194/ https://www.ncbi.nlm.nih.gov/pubmed/33643821 http://dx.doi.org/10.1016/j.apsb.2020.09.008

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