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Norlichexanthone purified from plant endophyte prevents postmenopausal osteoporosis by targeting ERα to inhibit RANKL signaling

Although different types of drugs are available for postmenopausal osteoporosis, the limitations of the current therapies including drug resistances and adverse effects require identification of novel anti-osteoporosis agents. Here, we defined that norlichexanthone (NOR), a natural product, is a lig...

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Detalles Bibliográficos
Autores principales: Wang, Keqi, Chen, Yongyan, Gao, Shuo, Wang, Maosi, Ge, Mengmeng, Yang, Qian, Liao, Mingkai, Xu, Lin, Chen, Junjie, Zeng, Zhiping, Chen, Haifeng, Zhang, Xiao-kun, Lin, Ting, Zhou, Hu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893202/
https://www.ncbi.nlm.nih.gov/pubmed/33643823
http://dx.doi.org/10.1016/j.apsb.2020.09.012