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Norlichexanthone purified from plant endophyte prevents postmenopausal osteoporosis by targeting ERα to inhibit RANKL signaling
Although different types of drugs are available for postmenopausal osteoporosis, the limitations of the current therapies including drug resistances and adverse effects require identification of novel anti-osteoporosis agents. Here, we defined that norlichexanthone (NOR), a natural product, is a lig...
Autores principales: | Wang, Keqi, Chen, Yongyan, Gao, Shuo, Wang, Maosi, Ge, Mengmeng, Yang, Qian, Liao, Mingkai, Xu, Lin, Chen, Junjie, Zeng, Zhiping, Chen, Haifeng, Zhang, Xiao-kun, Lin, Ting, Zhou, Hu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893202/ https://www.ncbi.nlm.nih.gov/pubmed/33643823 http://dx.doi.org/10.1016/j.apsb.2020.09.012 |
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