NOX4/Src regulates ANP secretion through activating ERK1/2 and Akt/GATA4 signaling in beating rat hypoxic atria

Nicotinamide adenine dinucleotide phosphate oxidases (NOXs) are the major enzymatic source of reactive oxygen species (ROS). NOX2 and NOX4 are expressed in the heart but its role in hypoxia-induced atrial natriuretic peptide (ANP) secretion is unclear. This study investigated the effect of NOX on AN...

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Detalles Bibliográficos
Autores principales: Wu, Cheng-zhe, Li, Xiang, Hong, Lan, Han, Zhuo-na, Liu, Ying, Wei, Cheng-xi, Cui, Xun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893495/
https://www.ncbi.nlm.nih.gov/pubmed/33602886
http://dx.doi.org/10.4196/kjpp.2021.25.2.159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893495/
https://www.ncbi.nlm.nih.gov/pubmed/33602886
http://dx.doi.org/10.4196/kjpp.2021.25.2.159

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