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NOX4/Src regulates ANP secretion through activating ERK1/2 and Akt/GATA4 signaling in beating rat hypoxic atria
Nicotinamide adenine dinucleotide phosphate oxidases (NOXs) are the major enzymatic source of reactive oxygen species (ROS). NOX2 and NOX4 are expressed in the heart but its role in hypoxia-induced atrial natriuretic peptide (ANP) secretion is unclear. This study investigated the effect of NOX on AN...
Autores principales: | Wu, Cheng-zhe, Li, Xiang, Hong, Lan, Han, Zhuo-na, Liu, Ying, Wei, Cheng-xi, Cui, Xun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Physiological Society and The Korean Society of Pharmacology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893495/ https://www.ncbi.nlm.nih.gov/pubmed/33602886 http://dx.doi.org/10.4196/kjpp.2021.25.2.159 |
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