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LY3214996 relieves acquired resistance to sorafenib in hepatocellular carcinoma cells

Background: Sorafenib, an oral multi-kinase inhibitor of rapidly accelerated fibrosarcoma; vascular endothelial growth factor receptor-2/3, platelet-derived growth factor receptor, c-Kit, and Flt-3 signaling, is approved for treatment of advanced hepatocellular carcinoma (HCC). However, the benefit...

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Detalles Bibliográficos
Autores principales: Ma, Yongfang, Xu, Ruyue, Liu, Xueke, Zhang, Yinci, Song, Li, Cai, Shuyu, Zhou, Shuping, Xie, Yinghai, Li, Amin, Cao, Weiya, Tang, Xiaolong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893555/
https://www.ncbi.nlm.nih.gov/pubmed/33628103
http://dx.doi.org/10.7150/ijms.51256