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Distinct profile of cell-free DNA in malignant pleural effusion of non-small cell lung cancer and its impact on clinical genetic testing

Cell-free DNA (cfDNA) in supernatant of pleural effusion from advanced NSCLC patients has been proved as surrogate sample detecting therapeutic targets as well as tumor mutation burden (TMB). As recently reported, cfDNA in pleural effusion supernatant is superior to plasma in TMB evaluation. It is r...

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Detalles Bibliográficos
Autores principales: Yu, Yongfeng, Qian, Jie, Shen, Lan, Ji, Wenxiang, Lu, Shun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893565/
https://www.ncbi.nlm.nih.gov/pubmed/33628109
http://dx.doi.org/10.7150/ijms.52306