Free CA125 promotes ovarian cancer cell migration and tumor metastasis by binding Mesothelin to reduce DKK1 expression and activate the SGK3/FOXO3 pathway

Objective: CA125/MUC16 is an O-glycosylated protein that is expressed on the surfaces of ovarian epithelial cells. This molecule is a widely used tumor-associated marker for diagnosis of ovarian cancer. Recently, CA125 was shown to be involved in ovarian cancer metastasis. The purpose of this study...

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Detalles Bibliográficos
Autores principales: Huo, Qianyu, Xu, Chen, Shao, Yanhong, Yu, Qin, Huang, Lunhui, Liu, Yunde, Bao, Huijing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893585/
https://www.ncbi.nlm.nih.gov/pubmed/33613114
http://dx.doi.org/10.7150/ijbs.52097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893585/
https://www.ncbi.nlm.nih.gov/pubmed/33613114
http://dx.doi.org/10.7150/ijbs.52097

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