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Effect of intermittent preventive treatment for malaria with dihydroartemisinin-piperaquine on immune responses to vaccines among rural Ugandan adolescents: randomised controlled trial protocol B for the ‘POPulation differences in VACcine responses’ (POPVAC) programme

INTRODUCTION: Drivers of lower vaccine efficacy and impaired vaccine-specific immune responses in low-income versus high-income countries, and in rural compared with urban settings, are not fully elucidated. Repeated exposure to and immunomodulation by parasite infections may be important. We focus...

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Detalles Bibliográficos
Autores principales: Natukunda, Agnes, Nkurunungi, Gyaviira, Zirimenya, Ludoviko, Nassuuna, Jacent, Oduru, Gloria, Amongin, Rebecca, Kabuubi, Prossy N, Mutebe, Alex, Onen, Caroline, Amongi, Susan, Nakazibwe, Esther, Akello, Florence, Kiwanuka, Samuel, Kiwudhu, Fred, Sewankambo, Moses, Nsubuga, Denis, Kizindo, Robert, Staedke, Sarah G, Cose, Stephen, Webb, Emily, Elliott, Alison M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893608/
https://www.ncbi.nlm.nih.gov/pubmed/33593769
http://dx.doi.org/10.1136/bmjopen-2020-040427