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The microRNA-429/DUSP4 axis regulates the sensitivity of colorectal cancer cells to nintedanib

Colorectal cancer (CRC) is recognized as one of the most common malignancies, which ranks third among all cancer-related deaths worldwide. Nintedanib is an orally available tyrosine kinase inhibitor that can treat CRC; however, drug resistance to nintedanib leads to unsatisfactory treatments for pat...

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Detalles Bibliográficos
Autores principales: Cheng, Guohua, Li, Yarong, Liu, Zhaoyu, Song, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893689/
https://www.ncbi.nlm.nih.gov/pubmed/33495832
http://dx.doi.org/10.3892/mmr.2021.11867