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Critical implication of the PTEN/PI3K/AKT pathway during BMP2-induced heterotopic ossification

Heterotopic ossification (HO) is characterized by extraskeletal ossification in soft tissue. Thus far, there is a lack of effective drug therapy against HO. Loss of PTEN in osteoblasts has been reported to accumulate bone mass in skeletal development and promote fracture healing in association with...

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Detalles Bibliográficos
Autores principales: Dong, Jun, Xu, Xiqiang, Zhang, Qingyu, Yuan, Zenong, Tan, Bingyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893754/
https://www.ncbi.nlm.nih.gov/pubmed/33537834
http://dx.doi.org/10.3892/mmr.2021.11893