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Astragaloside IV improves angiogenesis under hypoxic conditions by enhancing hypoxia-inducible factor-1α SUMOylation

Improving angiogenic capacity under hypoxic conditions is essential for improving the survival of skin grafts, as they often lack the necessary blood supply. The stable expression levels of hypoxia-inducible factor-1α (HIF-1α) in the nucleus directly affect the downstream vascular endothelial growth...

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Detalles Bibliográficos
Autores principales: Wang, Baoshen, Zhang, Chunyan, Chu, Dongmei, Ma, Xiaofang, Yu, Tian, Liu, Xiaozhi, Hu, Changqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893755/
https://www.ncbi.nlm.nih.gov/pubmed/33537820
http://dx.doi.org/10.3892/mmr.2021.11883