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(−)-Epigallocatechin-3-gallate Inhibits Human and Rat Renal Organic Anion Transporters

[Image: see text] Organic anion transporter 1 (OAT1, SLC22A6) and 3 (OAT3, SLC22A8) are multispecific drug transporters highly expressed on the basolateral membranes of the renal proximal tubules. OAT1 and OAT3 mediate the tubular secretion of clinically significant drugs; thus, they influence the p...

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Detalles Bibliográficos
Autores principales: Kawasaki, Tatsuya, Kondo, Masaki, Hiramatsu, Rioka, Nabekura, Tomohiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893792/
https://www.ncbi.nlm.nih.gov/pubmed/33623845
http://dx.doi.org/10.1021/acsomega.0c05586