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Functional interaction between macrophages and hepatocytes dictate the outcome of liver fibrosis

Hepatocytes and liver-resident macrophages known as Kupffer cells (KCs) are key cell types involved in liver fibrosis. The transcription factor c-Jun plays a fundamental role in regulating hepatocyte and macrophage functions. We have examined c-Jun’s role in the functional interaction of these cells...

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Detalles Bibliográficos
Autores principales: Xie, Min, Chia, Ren Hui, Li, Dan, Teo, Fanny Xueting, Krueger, Christian, Sabapathy, Kanaga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893818/
https://www.ncbi.nlm.nih.gov/pubmed/33514653
http://dx.doi.org/10.26508/lsa.202000803