Assessing optimal: inequalities in codon optimization algorithms

BACKGROUND: Custom genes have become a common resource in recombinant biology over the last 20 years due to the plummeting cost of DNA synthesis. These genes are often “optimized” to non-native sequences for overexpression in a non-native host by substituting synonymous codons within the coding DNA...

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Detalles Bibliográficos
Autores principales: Ranaghan, Matthew J., Li, Jeffrey J., Laprise, Dylan M., Garvie, Colin W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893858/
https://www.ncbi.nlm.nih.gov/pubmed/33607980
http://dx.doi.org/10.1186/s12915-021-00968-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893858/
https://www.ncbi.nlm.nih.gov/pubmed/33607980
http://dx.doi.org/10.1186/s12915-021-00968-8

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