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Assessing optimal: inequalities in codon optimization algorithms
BACKGROUND: Custom genes have become a common resource in recombinant biology over the last 20 years due to the plummeting cost of DNA synthesis. These genes are often “optimized” to non-native sequences for overexpression in a non-native host by substituting synonymous codons within the coding DNA...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893858/ https://www.ncbi.nlm.nih.gov/pubmed/33607980 http://dx.doi.org/10.1186/s12915-021-00968-8 |