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Global transcriptome profile of the developmental principles of in vitro iPSC-to-motor neuron differentiation

BACKGROUND: Human induced pluripotent stem cells (iPSC) have opened new avenues for regenerative medicine. Consequently, iPSC-derived motor neurons have emerged as potentially viable therapies for spinal cord injuries and neurodegenerative disorders including Amyotrophic Lateral Sclerosis. However,...

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Detalles Bibliográficos
Autores principales: Solomon, Emilia, Davis-Anderson, Katie, Hovde, Blake, Micheva-Viteva, Sofiya, Harris, Jennifer Foster, Twary, Scott, Iyer, Rashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893891/
https://www.ncbi.nlm.nih.gov/pubmed/33602141
http://dx.doi.org/10.1186/s12860-021-00343-z