Cargando…

Global transcriptome profile of the developmental principles of in vitro iPSC-to-motor neuron differentiation

BACKGROUND: Human induced pluripotent stem cells (iPSC) have opened new avenues for regenerative medicine. Consequently, iPSC-derived motor neurons have emerged as potentially viable therapies for spinal cord injuries and neurodegenerative disorders including Amyotrophic Lateral Sclerosis. However,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Solomon, Emilia, Davis-Anderson, Katie, Hovde, Blake, Micheva-Viteva, Sofiya, Harris, Jennifer Foster, Twary, Scott, Iyer, Rashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893891/ https://www.ncbi.nlm.nih.gov/pubmed/33602141 http://dx.doi.org/10.1186/s12860-021-00343-z

Ejemplares similares

CRISPR/Cas9 Directed Reprogramming of iPSC for Accelerated Motor Neuron Differentiation Leads to Dysregulation of Neuronal Fate Patterning and Function
por: Davis-Anderson, Katie, et al.
Publicado: (2023)

Optimization of Application-Driven Development of In Vitro Neuromuscular Junction Models
por: Strickland, Julie B., et al.
Publicado: (2022)

What Can Go Wrong When Applying Immune Modulation Therapies to Target Persistent Bacterial Infections
por: Micheva-Viteva, Sofiya, et al.
Publicado: (2020)

Small RNA-mediated regulation of host–pathogen interactions
por: Harris, Jennifer F, et al.
Publicado: (2013)

Banking on iPSC- Is it Doable and is it Worthwhile
por: Solomon, Susan, et al.
Publicado: (2014)

CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis
por: Samelson, Avi J., et al.
Publicado: (2023)

Classification of Developmental Toxicants in a Human iPSC Transcriptomics-Based Test
por: Cherianidou, Anna, et al.
Publicado: (2022)

PKC-η-MARCKS Signaling Promotes Intracellular Survival of Unopsonized Burkholderia thailandensis
por: Micheva-Viteva, Sofiya N., et al.
Publicado: (2017)

Microglia Influence Neurofilament Deposition in ALS iPSC-Derived Motor Neurons
por: Allison, Reilly L., et al.
Publicado: (2022)

Antidepressant Paroxetine Exerts Developmental Neurotoxicity in an iPSC-Derived 3D Human Brain Model
por: Zhong, Xiali, et al.
Publicado: (2020)

c-KIT signaling is targeted by pathogenic Yersinia to suppress the host immune response
por: Micheva-Viteva, Sofiya N, et al.
Publicado: (2013)

Gene Modulation with CRISPR-based Tools in Human iPSC-Cardiomyocytes
por: Han, Julie Leann, et al.
Publicado: (2023)

Roadblocks in the Path of iPSC to the Clinic
por: Garreta, Elena, et al.
Publicado: (2018)

iPSC Bioprinting: Where are We at?
por: Romanazzo, Sara, et al.
Publicado: (2019)

Maturing iPSC-Derived Cardiomyocytes
por: Tang, Bor Luen
Publicado: (2020)

iPSC for modeling neurodegenerative disorders
por: Valadez-Barba, Valeria, et al.
Publicado: (2020)

An Optimized Workflow to Generate and Characterize iPSC-Derived Motor Neuron (MN) Spheroids
por: Castellanos-Montiel, María José, et al.
Publicado: (2023)

Selection and verification of antibodies against the cytoplasmic domain of M2 of influenza, a transmembrane protein
por: Velappan, Nileena, et al.
Publicado: (2020)

Polymer modelling accurately predicts three-dimensional chromosome reorganization with a seasonal coronavirus infection
por: Singhal, Ankush, et al.
Publicado: (2023)

Pro-maturational Effects of Human iPSC-Derived Cortical Astrocytes upon iPSC-Derived Cortical Neurons
por: Hedegaard, Anne, et al.
Publicado: (2020)

Differential expression of small RNAs from Burkholderia thailandensis in response to varying environmental and stress conditions
por: Stubben, Chris J, et al.
Publicado: (2014)

Targeting the Bet-Hedging Strategy with an Inhibitor of Bacterial Efflux Capacity Enhances Antibiotic Efficiency and Ameliorates Bacterial Persistence In Vitro
por: Morales, Demosthenes, et al.
Publicado: (2022)

Human iPSC-Cardiomyocytes as an Experimental Model to Study Epigenetic Modifiers of Electrophysiology
por: Pozo, Maria R., et al.
Publicado: (2022)

Modeling Protein Aggregation and the Heat Shock Response in ALS iPSC-Derived Motor Neurons
por: Seminary, Emily R., et al.
Publicado: (2018)

Human iPSC co-culture model to investigate the interaction between microglia and motor neurons
por: Vahsen, Björn F., et al.
Publicado: (2022)

Large-scale differentiation of iPSC-derived motor neurons from ALS and control subjects
por: Workman, Michael J., et al.
Publicado: (2023)

iPSC-based model of viral infection
Publicado: (2012)

Chromatin looping is needed for iPSC induction
por: Hu, Ji-Fan, et al.
Publicado: (2014)

iPSC-MSCs and islet allograft tolerance
por: Wang, Tong-Song, et al.
Publicado: (2015)

Human iPSC banking: barriers and opportunities
por: Huang, Ching-Ying, et al.
Publicado: (2019)

Application of iPSC to Modelling of Respiratory Diseases
por: Calvert, Ben A., et al.
Publicado: (2020)

The Utilisation of Hydrogels for iPSC-Cardiomyocyte Research
por: Patel, Leena, et al.
Publicado: (2023)

Nuclear, Chloroplast, and Mitochondrial Genome Sequences of the Prospective Microalgal Biofuel Strain Picochlorum soloecismus
por: Gonzalez-Esquer, C. Raul, et al.
Publicado: (2018)

Decay in survival motor neuron and plastin 3 levels during differentiation of iPSC-derived human motor neurons
por: Boza-Morán, María G, et al.
Publicado: (2015)

Human iPSC-Derived 2D and 3D Platforms for Rapidly Assessing Developmental, Functional, and Terminal Toxicities in Neural Cells
por: Slavin, Ileana, et al.
Publicado: (2021)

iPSC-Based Models to Unravel Key Pathogenetic Processes Underlying Motor Neuron Disease Development
por: Faravelli, Irene, et al.
Publicado: (2014)

Quantitative comparison of the mRNA content of human iPSC‐derived motor neurons and their extracellular vesicles
por: Otake, Kentaro, et al.
Publicado: (2021)

Aryl Hydrocarbon Receptor (AhR)-Mediated Signaling in iPSC-Derived Human Motor Neurons
por: Imran, Saima Jalil, et al.
Publicado: (2022)

Specific vulnerability of iPSC-derived motor neurons with TDP-43 gene mutation to oxidative stress
por: Onda-Ohto, Asako, et al.
Publicado: (2023)

Identifying the dynamics of actin and tubulin polymerization in iPSCs and in iPSC-derived neurons
por: Magliocca, Valentina, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_tnpcpvoq2i5liog8ul6k0j6eha