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Autoantibodies Against Lysosome Associated Membrane Protein-2 (LAMP-2) in Pediatric Chronic Primary Systemic Vasculitis

BACKGROUND: Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a small vessel vasculitis in adults and children that commonly affects the kidneys. Although the frequent antigenic, and presumed pathogenic, targets of ANCA in AAV are proteinase-3 (PR3) and myeloperoxidase (MPO)...

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Detalles Bibliográficos
Autores principales: Gibson, Kristen M., Kain, Renate, Luqmani, Raashid A., Ross, Colin J., Cabral, David A., Brown, Kelly L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893977/
https://www.ncbi.nlm.nih.gov/pubmed/33613565
http://dx.doi.org/10.3389/fimmu.2020.624758