Combination of tumor necrosis factor‐α and epidermal growth factor induces the adrenergic‐to‐mesenchymal transdifferentiation in SH‐SY5Y neuroblastoma cells

Neuroblastoma, a type of cancer that is common in children, is composed of two genetically clonal but epigenetically distinct cell types: mesenchymal (MES) and adrenergic (ADRN) types, controlled by super‐enhancer‐associated lineage‐specific transcription factor networks. Mesenchymal‐type cells are...

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Detalles Bibliográficos
Autores principales: Huang, Yue, Tsubota, Shoma, Nishio, Nobuhiro, Takahashi, Yoshiyuki, Kadomatsu, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893981/
https://www.ncbi.nlm.nih.gov/pubmed/33277754
http://dx.doi.org/10.1111/cas.14760

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893981/
https://www.ncbi.nlm.nih.gov/pubmed/33277754
http://dx.doi.org/10.1111/cas.14760

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