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Combination of tumor necrosis factor‐α and epidermal growth factor induces the adrenergic‐to‐mesenchymal transdifferentiation in SH‐SY5Y neuroblastoma cells
Neuroblastoma, a type of cancer that is common in children, is composed of two genetically clonal but epigenetically distinct cell types: mesenchymal (MES) and adrenergic (ADRN) types, controlled by super‐enhancer‐associated lineage‐specific transcription factor networks. Mesenchymal‐type cells are...
Autores principales: | Huang, Yue, Tsubota, Shoma, Nishio, Nobuhiro, Takahashi, Yoshiyuki, Kadomatsu, Kenji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893981/ https://www.ncbi.nlm.nih.gov/pubmed/33277754 http://dx.doi.org/10.1111/cas.14760 |
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