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Therapeutic inhibition of polo‐like kinases in anaplastic thyroid cancer

Polo‐like kinases (PLKs) are potent regulators of cell proliferation and cell survival. Polo‐like kinases are potential targets in the treatment of anaplastic thyroid cancer (ATC), a rare but deadly disease. The therapeutic effects of volasertib, a PLK inhibitor, was evaluated for the treatment of A...

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Detalles Bibliográficos
Autores principales: Lin, Shu‐Fu, Yeh, Chun‐Nan, Huang, Yu‐Tung, Chou, Ting‐Chao, Wong, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893987/
https://www.ncbi.nlm.nih.gov/pubmed/33306266
http://dx.doi.org/10.1111/cas.14769