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Genomic destabilization and its associated mutagenesis increase with senescence‐associated phenotype expression
Cancer develops through multiple rounds of clonal evolution of cells with abrogated defense systems. Such clonal evolution is triggered by genomic destabilization with associated mutagenesis. However, what increases the risk of genomic destabilization remains unclear. Genomic instability is usually...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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John Wiley and Sons Inc.
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7893996/ https://www.ncbi.nlm.nih.gov/pubmed/33222327 http://dx.doi.org/10.1111/cas.14746 |