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Epigenetic modification‐dependent androgen receptor occupancy facilitates the ectopic TSPY1 expression in prostate cancer cells

Testis‐specific protein Y‐encoded 1 (TSPY1), a Y chromosome‐linked oncogene, is frequently activated in prostate cancers (PCa) and its expression is correlated with the poor prognosis of PCa. However, the cause of the ectopic transcription of TSPY1 in PCa remains unclear. Here, we observed that the...

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Detalles Bibliográficos
Autores principales: Leng, Xiangyou, Liu, Mohan, Tao, Dachang, Yang, Bo, Zhang, Yangwei, He, Tianrong, Xie, Shengyu, Wang, Zhaokun, Liu, Yunqiang, Yang, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894013/
https://www.ncbi.nlm.nih.gov/pubmed/33185915
http://dx.doi.org/10.1111/cas.14731