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Q-cubed mutant cues clues to CLC antiport mechanism
A new structure of a CLC antiporter mutant, along with EPR spectroscopy and computational dynamics, now resolves several basic puzzles regarding how these transporters stoichiometrically move Cl(−) and H(+) in opposite directions across biological membranes.
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Rockefeller University Press
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894039/ https://www.ncbi.nlm.nih.gov/pubmed/33600550 http://dx.doi.org/10.1085/jgp.202112868 |