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Q-cubed mutant cues clues to CLC antiport mechanism
A new structure of a CLC antiporter mutant, along with EPR spectroscopy and computational dynamics, now resolves several basic puzzles regarding how these transporters stoichiometrically move Cl(−) and H(+) in opposite directions across biological membranes.
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Rockefeller University Press
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894039/ https://www.ncbi.nlm.nih.gov/pubmed/33600550 http://dx.doi.org/10.1085/jgp.202112868 |
| _version_ | 1783653167312928768 |
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| author | Miller, Chris |
| author_facet | Miller, Chris |
| author_sort | Miller, Chris |
| collection | PubMed |
| description | A new structure of a CLC antiporter mutant, along with EPR spectroscopy and computational dynamics, now resolves several basic puzzles regarding how these transporters stoichiometrically move Cl(−) and H(+) in opposite directions across biological membranes. |
| format | Online Article Text |
| id | pubmed-7894039 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2021 |
| publisher | Rockefeller University Press |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-78940392021-10-05 Q-cubed mutant cues clues to CLC antiport mechanism Miller, Chris J Gen Physiol Commentary A new structure of a CLC antiporter mutant, along with EPR spectroscopy and computational dynamics, now resolves several basic puzzles regarding how these transporters stoichiometrically move Cl(−) and H(+) in opposite directions across biological membranes. Rockefeller University Press 2021-02-17 /pmc/articles/PMC7894039/ /pubmed/33600550 http://dx.doi.org/10.1085/jgp.202112868 Text en © 2021 Miller http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/). |
| spellingShingle | Commentary Miller, Chris Q-cubed mutant cues clues to CLC antiport mechanism |
| title | Q-cubed mutant cues clues to CLC antiport mechanism |
| title_full | Q-cubed mutant cues clues to CLC antiport mechanism |
| title_fullStr | Q-cubed mutant cues clues to CLC antiport mechanism |
| title_full_unstemmed | Q-cubed mutant cues clues to CLC antiport mechanism |
| title_short | Q-cubed mutant cues clues to CLC antiport mechanism |
| title_sort | q-cubed mutant cues clues to clc antiport mechanism |
| topic | Commentary |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894039/ https://www.ncbi.nlm.nih.gov/pubmed/33600550 http://dx.doi.org/10.1085/jgp.202112868 |
| work_keys_str_mv | AT millerchris qcubedmutantcuescluestoclcantiportmechanism |