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Predicting lung adenocarcinoma disease progression using methylation-correlated blocks and ensemble machine learning classifiers
Applying the knowledge that methyltransferases and demethylases can modify adjacent cytosine-phosphorothioate-guanine (CpG) sites in the same DNA strand, we found that combining multiple CpGs into a single block may improve cancer diagnosis. However, survival prediction remains a challenge. In this...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894106/ https://www.ncbi.nlm.nih.gov/pubmed/33628643 http://dx.doi.org/10.7717/peerj.10884 |