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Building up Pt(II)−Thiosemicarbazone−Lysine−sC18 Conjugates

Three chiral tridentate N^N^S coordinating pyridine‐carbaldehyde (S)‐N4‐(α‐methylbenzyl)thiosemicarbazones (HTSCmB) were synthesised along with lysine‐modified derivatives. One of them was selected and covalently conjugated to the cell‐penetrating peptide sC18 by solid‐phase peptide synthesis. The H...

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Detalles Bibliográficos
Autores principales: Haseloer, Alexander, Lützenburg, Tamara, Strache, Joss Pepe, Neudörfl, Jörg, Neundorf, Ines, Klein, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894172/
https://www.ncbi.nlm.nih.gov/pubmed/32909347
http://dx.doi.org/10.1002/cbic.202000564