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Discovery and Design of Family VIII Carboxylesterases as Highly Efficient Acyltransferases

Promiscuous acyltransferase activity is the ability of certain hydrolases to preferentially catalyze acyl transfer over hydrolysis, even in bulk water. However, poor enantioselectivity, low transfer efficiency, significant product hydrolysis, and limited substrate scope represent considerable drawba...

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Detalles Bibliográficos
Autores principales: Müller, Henrik, Godehard, Simon P., Palm, Gottfried J., Berndt, Leona, Badenhorst, Christoffel P. S., Becker, Ann‐Kristin, Lammers, Michael, Bornscheuer, Uwe T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894173/
https://www.ncbi.nlm.nih.gov/pubmed/33140887
http://dx.doi.org/10.1002/anie.202014169