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Thal protects against paraquat‐induced lung injury through a microRNA‐141/HDAC6/IκBα‐NF‐κB axis in rat and cell models

The protective functions of thalidomide in paraquat (PQ)‐induced injury have been reported. But the mechanisms remain largely unknown. In this research, a PQ‐treated rat model was established and further treated with thalidomide. Oedema and pathological changes, oxidative stress, inflammation, fibro...

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Detalles Bibliográficos
Autores principales: Zheng, Fenshuang, Zhu, Junbo, Zhang, Wei, Fu, Yangshan, Lin, Zhaoheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894280/
https://www.ncbi.nlm.nih.gov/pubmed/33015978
http://dx.doi.org/10.1111/bcpt.13505