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FKBP5 polymorphisms induce differential glucocorticoid responsiveness in primary CNS cells – First insights from novel humanized mice

The brain is a central hub for integration of internal and external conditions and, thus, a regulator of the stress response. Glucocorticoids are the essential communicators of this response. Aberrations in glucocorticoid signaling are a common symptom in patients with psychiatric disorders. The gen...

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Detalles Bibliográficos
Autores principales: Nold, Verena, Richter, Nadine, Hengerer, Bastian, Kolassa, Iris‐Tatjana, Allers, Kelly Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894319/
https://www.ncbi.nlm.nih.gov/pubmed/33030232
http://dx.doi.org/10.1111/ejn.14999