Ligation of 2′, 3′‐cyclic phosphate RNAs for the identification of microRNA binding sites

Identifying the targetome of a microRNA is key for understanding its functions. Cross‐linking and immunoprecipitation (CLIP) methods capture native miRNA‐mRNA interactions in cells. Some of these methods yield small amounts of chimeric miRNA‐mRNA sequences via ligation of 5′‐phosphorylated RNAs prod...

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Detalles Bibliográficos
Autores principales: Berk, Christian, Wang, Yuluan, Laski, Artur, Tsagkris, Stylianos, Hall, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Letters
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894349/
https://www.ncbi.nlm.nih.gov/pubmed/33113149
http://dx.doi.org/10.1002/1873-3468.13976

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894349/
https://www.ncbi.nlm.nih.gov/pubmed/33113149
http://dx.doi.org/10.1002/1873-3468.13976

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