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Ligation of 2′, 3′‐cyclic phosphate RNAs for the identification of microRNA binding sites
Identifying the targetome of a microRNA is key for understanding its functions. Cross‐linking and immunoprecipitation (CLIP) methods capture native miRNA‐mRNA interactions in cells. Some of these methods yield small amounts of chimeric miRNA‐mRNA sequences via ligation of 5′‐phosphorylated RNAs prod...
Autores principales: | Berk, Christian, Wang, Yuluan, Laski, Artur, Tsagkris, Stylianos, Hall, Jonathan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894349/ https://www.ncbi.nlm.nih.gov/pubmed/33113149 http://dx.doi.org/10.1002/1873-3468.13976 |
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