microRNA-130b downregulation potentiates chondrogenic differentiation of bone marrow mesenchymal stem cells by targeting SOX9

Osteoarthritis (OA) is a chronic health condition. MicroRNAs (miRs) are critical in chondrocyte apoptosis in OA. We aimed to investigate the mechanism of miR-130b in OA progression. Bone marrow mesenchymal stem cells (BMSCs) and chondrocytes were first extracted. Chondrogenic differentiation of BMSC...

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Detalles Bibliográficos
Autores principales: Zhang, Penggui, Gao, Guangming, Zhou, Ziyu, He, Xuejun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894390/
https://www.ncbi.nlm.nih.gov/pubmed/33624729
http://dx.doi.org/10.1590/1414-431X202010345

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894390/
https://www.ncbi.nlm.nih.gov/pubmed/33624729
http://dx.doi.org/10.1590/1414-431X202010345

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