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Concentration‐QTc Modeling of Ozanimod’s Major Active Metabolites in Adult Healthy Subjects
Ozanimod, approved by regulatory agencies in multiple countries for the treatment of adults with relapsing multiple sclerosis, is a sphingosine 1‐phosphate (S1P) receptor modulator, which binds with high affinity selectively to S1P receptor subtypes 1 and 5. The relationships between plasma concentr...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894403/ https://www.ncbi.nlm.nih.gov/pubmed/33314790 http://dx.doi.org/10.1002/psp4.12580 |