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Synergistic anti-tumor efficacy of oncolytic influenza viruses and B7-H3 immune- checkpoint inhibitors against IC-resistant lung cancers

Non-small cell lung cancers (NSCLCs) establish a highly immunosuppressive tumor microenvironment supporting cancer growth. To interfere with cancer-mediated immunosuppression, selective immune-checkpoint inhibitors (ICIs) have been approved as a standard-of-care treatment for NSCLCs. However, the ma...

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Detalles Bibliográficos
Autores principales: Masemann, Dörthe, Meissner, Ramona, Schied, Tanja, Lichty, Brian D, Rapp, Ulf R, Wixler, Viktor, Ludwig, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894418/
https://www.ncbi.nlm.nih.gov/pubmed/33643696
http://dx.doi.org/10.1080/2162402X.2021.1885778