Cargando…
Synergistic anti-tumor efficacy of oncolytic influenza viruses and B7-H3 immune- checkpoint inhibitors against IC-resistant lung cancers
Non-small cell lung cancers (NSCLCs) establish a highly immunosuppressive tumor microenvironment supporting cancer growth. To interfere with cancer-mediated immunosuppression, selective immune-checkpoint inhibitors (ICIs) have been approved as a standard-of-care treatment for NSCLCs. However, the ma...
Autores principales: | Masemann, Dörthe, Meissner, Ramona, Schied, Tanja, Lichty, Brian D, Rapp, Ulf R, Wixler, Viktor, Ludwig, Stephan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894418/ https://www.ncbi.nlm.nih.gov/pubmed/33643696 http://dx.doi.org/10.1080/2162402X.2021.1885778 |
Ejemplares similares
-
Oncolytic influenza virus infection restores immunocompetence of lung tumor-associated alveolar macrophages
por: Masemann, Dörthe, et al.
Publicado: (2018) -
PD-1 IC Inhibition Synergistically Improves Influenza A Virus-Mediated Oncolysis of Metastatic Pulmonary Melanoma
por: Sitnik, Siarhei, et al.
Publicado: (2020) -
Replication-incompetent influenza A viruses armed with IFN-γ effectively mediate immune modulation and tumor destruction in mice harboring lung cancer
por: Meissner, Ramona, et al.
Publicado: (2023) -
The LIM-Only Protein FHL2 Attenuates Lung Inflammation during Bleomycin-Induced Fibrosis
por: Alnajar, Abdulaleem, et al.
Publicado: (2013) -
In Vitro and In Vivo Antitumor Activity of a Novel Semisynthetic Derivative of Cucurbitacin B
por: Silva, Izabella T., et al.
Publicado: (2015)