Generation of metabolically functional hepatocyte‐like cells from dedifferentiated fat cells by Foxa2, Hnf4a and Sall1 transduction

Mature adipocyte‐derived dedifferentiated fat (DFAT) cells have been identified to possess similar multipotency to mesenchymal stem cells, but a method for converting DFAT cells into hepatocytes was previously unknown. Here, using comprehensive analysis of gene expression profiles, we have extracted...

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Detalles Bibliográficos
Autores principales: Hagiwara, Reiko, Oki, Yoshinao, Matsumaru, Takashi, Ibayashi, Shiho, Kano, Koichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894465/
https://www.ncbi.nlm.nih.gov/pubmed/33064855
http://dx.doi.org/10.1111/gtc.12814

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7894465/
https://www.ncbi.nlm.nih.gov/pubmed/33064855
http://dx.doi.org/10.1111/gtc.12814

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